In a medical first, a mother who received a uterus transplant from a dead donor gave birth to a healthy baby, researchers reported Wednesday.
The breakthrough operation, performed two years ago in Brazil, shows that such transplants are feasible and could help thousands of women unable to have children due to uterine problems, according to a study published in The Lancet medical journal.The baby girl was born in September 2016 in Sao Paolo.
Until recently, the only options available to women with so-called uterine infertility were adoption or the services of a surrogate mother.The first successful childbirth following uterine transplant from a living donor took place in 2013 in Sweden, and there have been 10 others since then.But there are far more women in need of transplants than there are potential live donors, so doctors wanted to find out if the procedure could work using the uterus of a woman who had died.
Ten attempts were made — in the United States, the Czech Republic, and Turkey — before the success reported Wednesday.Infertility affects 10- to 15 per cent of couples.Of this group, one in 500 women have problems with their uterus — due, for example, to a malformation, hysterectomy, or infection — that prevent them from becoming pregnant and carrying a child to term.”Our results provide a proof-of-concept for a new option for women with uterine infertility,” said Dani Ejzenberg, a doctor at the teaching hospital of the University of Sao Paulo.He describing the procedure as a “medical milestone”.
“The number of people willing and committed to donate organs upon their own death are far larger than those of live donors, offering a much wider potential donor population,” he said in a statement.The 32-year-old recipient was born without a uterus as a result of a rare syndrome.Four months before the transplant, she had in-vitro fertilisation resulting in eight fertilised eggs, which were preserved through freezing.The donor was a 45-year-old woman who died from a stroke.
Her uterus was removed and transplanted in surgery that lasted more than ten hours.The surgical team had to connect the donor’s uterus with the veins, arteries, ligaments, and vaginal canal of the recipient.To prevent her body from rejecting the new organ, the woman was given five different drugs, along with antimicrobials, anti-blood clotting treatments, and aspirin.After five months, the uterus showed no sign of rejection, ultrasound scans were normal, and the woman was menstruating regularly.
The fertilised eggs were implanted after seven months. Ten days later, doctors delivered the good news: she was pregnant.Besides a minor kidney infection — treated with antibiotics — during the 32nd week, the pregnancy was normal. After nearly 36 weeks a baby girl weighing 2.5 kilogrammes (about six pounds) was delivered via caesarean section.
Mother and baby left the hospital three days later.The transplanted uterus was removed during the C-section, allowing the woman to stop taking the immunosuppressive drugs.At age seven months and 12 days — when the manuscript reporting the findings was submitted for publication — the baby was breastfeeding and weighed 7.2 kilogrammes.
“We must congratulate the authors,” commented Dr. Srdjan Saso, an honorary clinical lecturer in obstetrics and gynaecology at Imperial College London, describing the findings as “extremely exciting”.Richard Kennedy, president of the International Federation of Fertility Societies, also welcomed the announcement but sounded a note of caution.”Uterine transplant is a novel technique and should be regarded as experimental,” he said.
NASA’s job offering: Rs. 6 lakh/month for staying in bed
NASA has got a new job opening, one that pays very well and only requires you to stay in bed.Yes, we know it sounds too good to be true, but the fact is, the space agency is actually offering Rs. 12 lakh (16,500 euros) for the job.
All you have to do is lie in a bed for 2 months straight.
NASA wants to investigate microgravity’s effect, potential solutions
Prolonged space travel can have side effects on the human body, including problems like muscle and bone breakdown and movement of fluids into the head.
This is why NASA and the European Space Agency are looking for 24 volunteers to investigate these problems and their countermeasures.
These participants will have to stay bed-ridden in a room for 60 days to closely simulate microgravity’s impact
With Gaganyaan, ISRO’s race to the top gains velocity
The Indian Space Research Organisation (ISRO) has begun the year 2019 with a bang. Not only has the space agency announced a slew of missions, including the much-awaited lunar lander, Chandrayaan-2, slated for 2019, but has set its sight high with its most ambitious project — the human space mission, Gaganyaan. While announcing the timeline for the human flight targeted at the end of 2021, ISRO chief K Sivan made two important comments. In the context of setting up a new vertical within the agency — the Human Space Flight Centre — he said the agency was looking beyond the first human flight. He said, “We are going to continue this programme in terms of a space station and human to the moon.” The second noteworthy comment from the space agency head was that India would be on a par with China with the human space flight.
Taken together, the comments amount to a marked strategic shift in India’s approach to space and point to the process of maturing of ISRO as a global player in the space arena. Clearly, the agency has recognised the need for human missions as a worthwhile goal to pursue over the long-term as a logical extension of its activities till now. It has also made it apparent that it is joining the undeclared space race with China.
When India took baby steps to become a space faring nation, Yuri Gagarin had already become the first human to have travelled to space in April 1961, and by the time ISRO took birth, the first human had landed on the moon. Since India’s forays into space began against the backdrop of a bitter space race between America and the Soviet Union, the founding father of the space programme, Vikram Sarabhai, had to declare that “we do not have the fantasy of competing with the economically advanced nations in the exploration of the moon or the planets or manned spaceflight”. Instead, he wanted India to use space technology to solve “real problems of man and society”.
After having followed Sarabhai’s vision for four decades during which ISRO contributed immensely to nation’s development, the agency has finally decided to turn the “fantasy” of a manned space flight into reality. This is definitely a shift because after the first Indian, Rakesh Sharma, was propelled into space aboard Soyuz T-11 in April 1984, participation in international manned missions or planning its own human flights were not on ISRO’s agenda. In fact, human flight was first discussed in India in 2004 — a year after China had sent its first human spaceflight. In 2006, ISRO formally discussed the idea with a group of external experts, and began working on some building block technologies needed for the mission as pre-project activity with seed money allocated in subsequent budgets.
India has been building its space capabilities in a step by step manner, working simultaneously on making rockets, fabricating satellites and developing applications. In parallel, it has a very strong presence in space science, having delivered successful missions to the moon, Mars and a space telescope AstroSat. The lunar orbiter, Chandrayaan, and the astronomy satellite have led to some spectacular scientific discoveries using home-made instruments. The Mars Orbiter Mission was a technology demonstrator. On the other hand, China, which began its space programme much later, went ahead more aggressively. It focused on military applications, human flight and building a space station, with an eye on projecting itself as a competitor to NASA. It has few space science achievements worth mentioning. Clearly, the Indian and Chinese programmes have grown so far with different goals and philosophies. In space applications and space science, India is ahead of China. But in human flights, China has taken a lead having demonstrated its prowess with as many as six successful missions, including operations like space walk and docking with its under-construction space station.
ISRO and its leadership are well justified in projecting their ambitions with regard to human flights vis-à-vis China, but these ambitions will need political backing beyond the first human flight planned for December 2021. Though a late entrant in human flights, ISRO may be up to some surprises up its sleeves, as it did with Chandrayaan-1 and the Mars mission. Sniffing signatures of water molecule on the moon by Chandrayaan-1 four decades after man landed there and stringing a spacecraft straight to the Red planet in first attempt are no mean achievements. For ISRO, the race may have has just begun.
ISRO Chairman on space war with China, preparations for Chandrayaan 2 and Gaganayan
Indian Space Research Organisation (ISRO) Chairman Kailasavadivoo Sivan has said when it comes to India Vs China debate in space sector, India is at par with China. This comes days after China landed Chang’e-4 lunar probe on the dark side of the moon and ahead of India’s Chandrayaan 2 mission which will be launched this year. Speaking to our correspondent Sidhant Sibal, he also spoke on Gaganayaan and ISRO’s focus for 2019.
Q: What will be your focus this year?
K Sivan: Focus this year is mainly on reaching out to children, students and we want them to be more and more aware of ISRO’s programmes. We want to bring students for young scientists programme. Student satellite is being launched-Kalamsat. Along with this outreach programme, we have incubation centres. These are for spreading the wings of ISRO. Along with this, we have priority for Gaganyaan. We have 32 missions to be completed this year.
Q: We are going to launch Chandrayaan 2 this year. Weeks ago, China landed a rover on the dark side of moon. What is the difference?
K Sivan: Chinese have landed on the dark side of the moon. We are going to land on the light side of the moon. Only thing is we are landing where nobody else has gone. Going closer to the south pole, where nobody has gone.
Q: Your reaction to China vs India space debate?
K Sivan: Regarding the tech part, we are on par with them.
Q: How are we helping the South Asian region?
K Sivan: We have one south asia satellite. We are giving one transponder free of cost to each country. Bhutan, Nepal, Afghanistan, Sri Lanka and the Maldives are making use of these. We are happy to note they are using satellite for the benefit of their country
Q: On Gaganyaan, are we taking help of countries?
K Sivan: On Gaganayan, many countries are ready to help us. France, Russia is ready to help. We will make use of everybody’s expertise to our benefit. Nasa is also willing to extend cooperation. We want to make use of everyone’s help for maximum benefit
Private FM channels to be permitted to broadcast AIR news
Private FM channels will be allowed to broadcast All India Radio news in English and Hindi after the Ministry of Information and Broadcasting Tuesday launched the facility.
The FM channels will have to carry the AIR news in an unaltered format and the service will be available free of cost on a trial basis till May 31 this year.
Gaganyaan project: Three Indians to spend a week in space, to cost Rs 10,000 crores
The Union Cabinet Friday approved the Gaganyaan project under which a three-member crew will be sent to space for seven days, Union Minister Ravi Shankar Prasad said.The project will cost Rs 10,000 crore, he said at a press conference here.
The Gaganyaan project was announced by Prime Minister Narendra Modi in his Independence Day speech.He had said the mission will be undertaken by 2022.India has already inked agreements with Russia and France for assistance in the ambitious project.
The Union Cabinet chaired by Prime Minister Shri Narendra Modi has approved the Gaganyaan Programme with demonstration of Indian Human Spaceflight capability to low earth orbit for a mission duration ranging from one orbital period to a maximum of seven days. A human rated GSLV Mk-lll will be used to carry the orbital module which will have necessary provisions for sustaining a 3-member crew for the duration of the mission. The necessary infrastructure for crew training, realization of flight systems and ground infrastructure will be established to support the Gaganyaan Programme. ISRO will collaborate extensively with National agencies, laboratories, academia and industry to accomplish the Gaganyaan Programme objectives.
The total fund requirement for the Gaganyaan Programme is within Rs.10,000 crore and includes cost of technology development, flight hardware realization and essential infrastructure elements. Two unmanned flights and one manned flight will be undertaken as part of Gaganyaan Programme.
Good news: Noida’s Aqua Line gets go ahead from NMRC, seeks inauguration date from govt
A final and mandatory safety inspection report has given the Noida Metro Rail Corporation (NMRC) the approval to launch commercial operations of the Aqua Line, officials said Friday.
With the approval, the NMRC has now written to the Uttar Pradesh government to finalise the date of inauguration of the much-awaited Aqua Line that would run between Sector 71 station in Noida and the Depot Station in Greater Noida, covering 29.7 km through 21 stations.
“The Commissioner of Metro Rail Safety (CMRS) report has been received and it has its sanction for the commercial operations of the metro service. The report also praised the civil and track work of the metro system, NMRC Executive Director P D Upadhyay said.
NMRC’s managing director has written to the state government for finalizing the date of inauguration, said Upadhyay, who was in Lucknow Friday, handed over a letter to Chief Secretary Anup Chandra Pandey.
He also said the fares of the Aqua Line would be decided in the NMRC Board meeting scheduled on December 28.
“Chairman Sanjay K Murthy, the additional secretary to the Ministry of Housing and Urban Affairs will chair the meeting, he added.
Earlier, the Greater Noida Industrial Development Authority (GNIDA) approved the second phase of the Metro link from Noida Sector 71 to Knowledge Park 5 in Greater Noida.
The extension will comprise nine stations and with a project cost of cost Rs 2,602 crores.
This decision was taken at the Authority’s 113th board meeting. “NMRC would be the nodal agency for the project. The first phase of the Metro project comprising five stations from Noida Sector 71 to Greater Noida Sector 2 is expected to cost around Rs 1521 crore, officials said.
The extended line of Noida Metro’s aqua line will have a total of nine metro stations out of which two will be in Noida and seven will be in Greater Noida. The metro stations in Noida include sectors 122 and 123 and the metro stations in Greater Noida include sector 4, Ecotech 12, sectors 2, 3, 10, 12 and Knowledge Park V.
Akhilesh Yadav earlier had given its approval for construction of a 15-km Metro project.
“We have asked builders to contribute fund and generate ideas to lure investment and buyers,” said a senior official of UP government.
“We are adhering to the direction of the government. This project will change the fortune of this belt. We have decided to plan stress-free homes where we will offer facilities for all family members,” said Rahul Gupta, Director of Ace group.
“We believe that this project is crucial as it will benefit thousands of homebuyers who have shifted to the newly built apartment complexes in Greater Noida West and nearby Crossings Republik in Ghaziabad that has 36,000 housing units,” said Geetambar Anand, CMD, ATS.
Greater Noida West has around 3.5 lakh under-construction housing units of which around 40,000 are occupied.
Winter solstice 2018: Here’s everything you need to know about the shortest day of the year
Today is the shortest day of the year, also known as the winter solstice. If you are not aware, Winter solstice marks the shortest day and longest night of the year. This time it is even more special since skywatchers will also have an opportunity to witness a Full moon and meteor shower.
What does solstice mean?
The term ‘solstice’ is derived from two Latin words “sol” which means sun, and “sistere”, meaning standstill. The Sun seems to stand still in the winter sky, marking the shortest day and longest night of the year.
What is Winter Solstice?
To talk about the science behind winter solstice, it marks the shortest day in the Northern Hemisphere since the sun is positioned at its most southerly position while directly overheating at the Tropic of Capricorn. On the other hand, the winter solstice also marks the longest day of in the Southern Hemisphere.
Winter Solstice 2018 date and time?
Just like every year, Winter solstice 2018 will also take place on December 21 and the exact timing for the 2018 winter solstice is 22:23 UTC (4:53 pm IST on December 22). As mentioned above, this Winter solstice 2018 is even more special as less than the day after the solstice, we will be able to see the last Full Moon of the year.
- On December 22 at 17:49 UTC, people will be able to see the last full moon of the year. The last full moon of the year is also known as Cold Full Moon, Long Night Moon and Cold Moon around the globe.
Srinagar shivers at minus 4.6 deg C, Kargil coldest in J-K at minus 15.8 deg C
Kargil in Ladakh region was the coldest place in Jammu and Kashmir Monday as minimum temperature dipped to minus 15.8 degree Celsius, MeT Office said Tuesday.
Cold conditions continued in Kashmir valley and Ladakh, while there was some respite in the Jammu region.
The mercury in Leh dipped to minus 15.1 degree Celsius. In Srinagar, the night temperature settled at a low of minus 4.6 degree Celsius. Qazigund recorded a minus 5.3 degree Celsius, Kokernag town was at minus 4.8 degree Celsius, Kupwara recorded minus 5.9 degree Celsius, Pahalgam settled at minus 7.7 degree Celsius, the ski-resort of Gulmarg recorded a minus 7.6 degree Celsius, the weather office said.
The valley will experience dry weather for the week ahead, MeT department said.
However, in Jammu the night temperature improved slightly after continuous dip over the past week.
Jammu city recorded an increase of 0.7 degree celsius in the night temperature to settle at 5.1 degree Celsius, a MeT official said. Despite the slight improvement, the night temperature continued to remain four degrees below normal levels.
Places in the region also experienced marginal increase in night temperatures. Bhadarwah of Doda district recorded a low of 0.6 degree Celsius against the previous night’s minus 1.2 degree Celsius, he said.
Katra, the base camp for the pilgrims visiting Vaishno Devi shrine, recorded a minimum of 6.5 degree Celsius, while Batote town along Jammu-Srinagar national highway registered a night temperature of 3.6 degree Celsius, he said.
However, the nearby highway town of Banihal, recorded a dip in the night temperature which settled at 0.7 degrees Celsius, the spokesman said.
Scientists preparing to search for life on Jupiter’s moon Europa
Scientists are designing a nuclear-powered “tunnelbot” that can penetrate through the icy shell of Jupiter’s moon Europa and search for signs of life in its sub-surface ocean.
Between 1995 and 2003, NASA’s Galileo spacecraft made several flybys of Jupiter’s moon, Europa. Several findings from observations of the moon pointed to evidence of a liquid ocean beneath Europa’s icy surface.
Researchers believe that the ocean could harbour microbial life, or evidence of now-extinct microbial life.
While scientists generally agree on where to look — underneath the thick, planet-wide ice shell where water is in contact with a rocky core and where biochemical ingredients for life may exist — how to get there to collect samples remains a major tactical problem.
“Estimates of the thickness of the ice shell range between 2 and 30 kilometers, and is a major barrier any lander will have to overcome in order to access areas we think have a chance of holding biosignatures representative of life on Europa,” said Andrew Dombard, associate professor at the University of Illinois at Chicago in the US.
Dombard and his team are tasked with designing technology and solutions for space exploration and science missions.
The group performed a concept study for a nuclear-powered “tunnelbot” that can penetrate the ice shell and reach the top of Europa’s ocean while carrying devices and instruments that can be used to search for signs of life or extinct life.
The bot would also evaluate the habitability of the ice shelf itself.
“We didn’t worry about how our tunnelbot would make it to Europa or get deployed into the ice. We just assumed it could get there and we focused on how it would work during descent to the ocean,” said Dombard.
The bot would sample ice throughout the shell, as well as water at the ice-water interface, and would look at the underside of the ice to search for microbial biofilms.
The bot would also have the capability of searching liquid water “lakes” within the ice shell.
The researchers considered two designs for their bot: one powered by a small nuclear reactor, and the other powered by General Purpose Heat Source bricks — radioactive heat source modules designed for space missions.
Heat from both these sources could be used to melt the ice shell. Communications would be provided by a string of “repeaters” connected to the bot by fibre optic cables, researchers said.
Indian Navy inducts deep submergence rescue vehicle into service
The Indian Navy Wednesday inducted the ‘Deep Submergence Rescue Vehicle’ into service at the Western Naval Command here.
Chief of the Naval Staff Admiral Sunil Lanba inducted the vehicle into the Navy.
“The induction of the vehicle has put the Indian Navy into a small league of world navies that have an integral submarine rescue capability,” a statement issued by the defence force read.
The Navy successfully concluded maiden trials of the Deep Submergence Rescue Vehicle (DSRV) on October 15, it said.
The vehicle can rescue as many as 14 people in one dive, a Navy official said.
The DSRV carried out underwater mating with a bottomed submarine, at a depth of over 300 feet. On successful mating, the DSRV opened its hatches and the submarine hatches and carried out transfer of personnel from the submarine to the DSRV, the Navy said.
These sea trials have proven the newly inducted DSRV’s ability to undertake rescue operations from disabled submarines at sea and provided the Navy with a critical capability, it said.
During the trials, the DSRV also dived successfully up to 666 metres, which is a record for deepest submergence by a ‘manned vessel’ in Indian waters.
The DSRV crew carried out remotely operated vehicle operations at a depth of over 750 metres and side scan sonar operations at a depth of over 650 metres, which are all ‘firsts’ for the Indian Navy, the statement said.PTI
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